Theoretical Formulation of Principal Components Analysis to Detect and Correct for Population Stratification
نویسندگان
چکیده
منابع مشابه
Theoretical Formulation of Principal Components Analysis to Detect and Correct for Population Stratification
The Eigenstrat method, based on principal components analysis (PCA), is commonly used both to quantify population relationships in population genetics and to correct for population stratification in genome-wide association studies. However, it can be difficult to make appropriate inference about population relationships from the principal component (PC) scatter plot. Here, to better understand ...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2010
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0012510